JAK1-IN-8
Modify Date: 2025-08-20 13:12:43
JAK1-IN-8 structure
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Common Name | JAK1-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 1973485-18-5 | Molecular Weight | 442.51 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C22H23FN4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JAK1-IN-8JAK1-IN-8, a potent JAK1 inhibitor (IC50<500 nM), compound 28, extracted from patent WO2016119700A1[1]. |
| Name | N-(5-{4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]-3-fluorophenyl}imidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | JAK1-IN-8, a potent JAK1 inhibitor (IC50<500 nM), compound 28, extracted from patent WO2016119700A1[1]. |
|---|---|
| Related Catalog | |
| Target |
JAK1:<500 nM (IC50) JAK2:500-1000 nM (IC50) JAK3:>5000 nM (IC50) |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C22H23FN4O3S |
| Molecular Weight | 442.51 |
| Exact Mass | 442.147491 |
| LogP | 1.05 |
| Index of Refraction | 1.712 |
| N-(5-{4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]-3-fluorophenyl}imidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide |
| MFCD30530428 |
| Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]-3-fluorophenyl]imidazo[1,2-a]pyridin-2-yl]- |