PTP1B-IN-5b
Modify Date: 2024-08-09 08:05:59
PTP1B-IN-5b structure
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Common Name | PTP1B-IN-5b | ||
|---|---|---|---|---|
| CAS Number | 2101230-45-7 | Molecular Weight | 417.479 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H19NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PTP1B-IN-5bPTP1B-IN-5b is a potent protein tyrosine phosphatase PTP1B inhibitor with IC50 of 5.25 uM; shows remarkable cytotoxic activity at 0.09 uM of IC50 against the MCF-7 cell line; also showed potential anticancer activity against MCF-7 (IC50=2.22 uM) and HepG2 (IC50=0.72 uM) cell lines as well as PTP1B inhibitory activity with IC50 of 6.37 uM. |
| Name | PTP1B-IN-5b |
|---|
| Description | PTP1B-IN-5b is a potent protein tyrosine phosphatase PTP1B inhibitor with IC50 of 5.25 uM; shows remarkable cytotoxic activity at 0.09 uM of IC50 against the MCF-7 cell line; also showed potential anticancer activity against MCF-7 (IC50=2.22 uM) and HepG2 (IC50=0.72 uM) cell lines as well as PTP1B inhibitory activity with IC50 of 6.37 uM. |
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| References | References 1. Gulipalli KC, et al.Bioorg Med Chem Lett. 2017 Aug 1;27(15):3558-3564. View Related Products by Target Protein Phosphatase/PTP |
| Molecular Formula | C24H19NO4S |
|---|---|
| Molecular Weight | 417.479 |