![]() HA-100 hydrochloride structure
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Common Name | HA-100 hydrochloride | ||
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CAS Number | 210297-47-5 | Molecular Weight | 350.26 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C13H17Cl2N3O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of HA-100 hydrochlorideHA-100 dihydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK inhibitor[1][2]. |
Name | 5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride |
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Synonym | More Synonyms |
Description | HA-100 dihydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK inhibitor[1][2]. |
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Related Catalog | |
Target |
PKA:8 μM (IC50) PKC:12 μM (IC50) PKC:6.5 μM (Ki) PKG:4 μM (IC50) MLCK:240 μM (IC50) MLCK:61 μM (Ki) |
References |
Molecular Formula | C13H17Cl2N3O2S |
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Molecular Weight | 350.26 |
Exact Mass | 349.041840 |
PSA | 70.68000 |
LogP | 3.78020 |
Isoquinoline, 5-(1-piperazinylsulfonyl)-, hydrochloride (1:2) |
5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride |