DBCO-PEG4-acid

Modify Date: 2025-08-26 17:37:16

DBCO-PEG4-acid Structure
DBCO-PEG4-acid structure
Common Name DBCO-PEG4-acid
CAS Number 2110448-99-0 Molecular Weight 552.62
Density N/A Boiling Point N/A
Molecular Formula C30H36N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG4-acid


DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG4-acid

 DBCO-PEG4-acid Biological Activity

Description DBCO-PEG4-acid is a a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C30H36N2O8
Molecular Weight 552.62
InChIKey NSVSVWJDGZGQGL-UHFFFAOYSA-N
SMILES O=C(O)CCOCCOCCOCCOCCC(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc21
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