VU 6010572 structure
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Common Name | VU 6010572 | ||
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CAS Number | 2126784-39-0 | Molecular Weight | 339.366 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C20H18FNO3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of VU 6010572A potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM; show no inhibition for mGlu2 (IC50>30 uM); displays improved physiochemical properties and in vivo efficacy in a mouse tail suspension test (MED = 3 mg/kg i.p.). |
Name | VU 6010572 |
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Description | A potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM; show no inhibition for mGlu2 (IC50>30 uM); displays improved physiochemical properties and in vivo efficacy in a mouse tail suspension test (MED = 3 mg/kg i.p.). |
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References | References 1. Engers JL, et al. ACS Med Chem Lett. 2017 Aug 15;8(9):925-930. View Related Products by Target mGluR |
Molecular Formula | C20H18FNO3 |
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Molecular Weight | 339.366 |