AZD-5991 S-enantiomer

Modify Date: 2024-01-09 21:25:46

AZD-5991 S-enantiomer structure	Common Name	AZD-5991 S-enantiomer
	CAS Number	2143061-82-7	Molecular Weight	672.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₃₄ClN₅O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AZD-5991 S-enantiomer

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

Name	AZD-5991 S-enantiomer

Description	AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	Mcl-1:6.3 μM (IC50) Mcl-1:0.98 μM (Kd)
References	[1]. Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.

Molecular Formula	C₃₅H₃₄ClN₅O₃S₂
Molecular Weight	672.26

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AZD-5991 (S-enantiomer)
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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