AZD-5991 S-enantiomer

Modify Date: 2024-01-09 21:25:46

AZD-5991 S-enantiomer structure	Common Name	AZD-5991 S-enantiomer
	CAS Number	2143061-82-7	Molecular Weight	672.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₃₄ClN₅O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AZD-5991 S-enantiomer

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

Name	AZD-5991 S-enantiomer

Description	AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	Mcl-1:6.3 μM (IC50) Mcl-1:0.98 μM (Kd)
References	[1]. Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.

Molecular Formula	C₃₅H₃₄ClN₅O₃S₂
Molecular Weight	672.26

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AZD-5991 (S-enantiomer)
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Purity: 98.0%
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AZD-5991 S-enantiomer Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.