BMS 753
Modify Date: 2025-08-27 14:21:33
BMS 753 structure
|
Common Name | BMS 753 | ||
|---|---|---|---|---|
| CAS Number | 215307-86-1 | Molecular Weight | 351.39600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H21NO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of BMS 753BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM[1]. |
| Name | 4-{[(1,1,3,3-Tetramethyl-2-oxo-2,3-dihydro-1H-inden-5-yl)carbonyl ]amino}benzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
RARα |
| In Vitro | BMS 753 results in low levels of RARβ transcripts in WT cells, RARγ-/-, but not activates in RARa-/- cells[1]. |
| References |
| Molecular Formula | C21H21NO4 |
|---|---|
| Molecular Weight | 351.39600 |
| Exact Mass | 351.14700 |
| PSA | 83.47000 |
| LogP | 3.84800 |
| InChIKey | KFBPBWUZXBYJDG-UHFFFAOYSA-N |
| SMILES | CC1(C)C(=O)C(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 |
| Pentanoic acid,5-[[bis(diethoxyphosphinyl)methyl]amino]-5-oxo |
| 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino] benzoic acid |
| 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]-benzoic acid |
| 4-[(Z)-2-ethoxyvinyl]-2-(methylthio)-5-pyrimidinecarbonitrile |
| 4-[(tetraethylbisphosphonomethyl)carbamoyl]butanoic acid |