Thalidomide-O-C6-COOH
Modify Date: 2024-01-04 16:11:32
Thalidomide-O-C6-COOH structure
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Common Name | Thalidomide-O-C6-COOH | ||
|---|---|---|---|---|
| CAS Number | 2169266-69-5 | Molecular Weight | 402.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H22N2O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-O-C6-COOHThalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-O-C6-COOH |
|---|---|
| Synonym | More Synonyms |
| Description | Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C20H22N2O7 |
|---|---|
| Molecular Weight | 402.40 |
| Hazard Codes | Xi |
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| MFCD32063464 |