Mal-amido-PEG9-NHBoc

Modify Date: 2024-01-09 21:35:01

Mal-amido-PEG9-NHBoc Structure
Mal-amido-PEG9-NHBoc structure
Common Name Mal-amido-PEG9-NHBoc
CAS Number 2182602-20-4 Molecular Weight 707.81
Density N/A Boiling Point N/A
Molecular Formula C32H57N3O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-amido-PEG9-NHBoc


Mal-amido-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-amido-PEG9-NH-Boc

 Mal-amido-PEG9-NHBoc Biological Activity

Description Mal-amido-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C32H57N3O14
Molecular Weight 707.81