TCO-PEG9-maleimide

Modify Date: 2024-01-04 19:40:08

TCO-PEG9-maleimide Structure
TCO-PEG9-maleimide structure
Common Name TCO-PEG9-maleimide
CAS Number 2183440-37-9 Molecular Weight 759.88
Density N/A Boiling Point N/A
Molecular Formula C36H61N3O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCO-PEG9-maleimide


TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TCO-PEG9-maleimide

 TCO-PEG9-maleimide Biological Activity

Description TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C36H61N3O14
Molecular Weight 759.88