PI3Ka-IN-5

Modify Date: 2025-08-26 14:11:27

PI3Ka-IN-5 Structure
PI3Ka-IN-5 structure
Common Name PI3Ka-IN-5
CAS Number 2237953-19-2 Molecular Weight 601.66
Density N/A Boiling Point N/A
Molecular Formula C30H35N9O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3Ka-IN-5


PI3Ka-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer[1].

 Names

Name PI3Ka-IN-5

 PI3Ka-IN-5 Biological Activity

Description PI3Ka-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer[1].
Related Catalog
Target

PI3Kα:0.7 nM (IC50)

mTOR:3.3 nM (IC50)

References

[1]. Wu CF, et, al. Synthesis and bioevaluation of diaryl urea derivatives as potential antitumor agents for the treatment of human colorectal cancer. Eur J Med Chem. 2022 Feb 5;229:114055.

 Chemical & Physical Properties

Molecular Formula C30H35N9O5
Molecular Weight 601.66
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