Azido-PEG3-chloroacetamide

Modify Date: 2024-01-13 11:02:15

Azido-PEG3-chloroacetamide Structure
Azido-PEG3-chloroacetamide structure
Common Name Azido-PEG3-chloroacetamide
CAS Number 604766-23-6 Molecular Weight 294.74
Density N/A Boiling Point N/A
Molecular Formula C10H19ClN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG3-chloroacetamide


Azido-PEG3-chloroacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG3-chloroacetamide

 Azido-PEG3-chloroacetamide Biological Activity

Description Azido-PEG3-chloroacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H19ClN4O4
Molecular Weight 294.74
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