CL2-SN-38

Modify Date: 2025-08-27 15:05:51

CL2-SN-38 Structure
CL2-SN-38 structure
Common Name CL2-SN-38
CAS Number 1036969-20-6 Molecular Weight 1626.80
Density N/A Boiling Point N/A
Molecular Formula C83H107N11O23 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL2-SN-38


CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types[1].

 Names

Name CL2-SN-38

 CL2-SN-38 Biological Activity

Description CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types[1].
Related Catalog
References

[1]. Cardillo TM, et al. Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. Clin Cancer Res. 2011 May 15;17(10):3157-69.

 Chemical & Physical Properties

Molecular Formula C83H107N11O23
Molecular Weight 1626.80
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