Epitinib succinate

Modify Date: 2024-01-09 11:21:55

Epitinib succinate Structure
Epitinib succinate structure
Common Name Epitinib succinate
CAS Number 2252334-12-4 Molecular Weight 548.59
Density N/A Boiling Point N/A
Molecular Formula C28H32N6O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Epitinib succinate


Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer[1][2].

 Names

Name Epitinib succinate

 Epitinib succinate Biological Activity

Description Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer[1][2].
Related Catalog
Target

EGFR[2]

In Vitro Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration[1][2].
References

[1]. Zhou et al. The safety profile of a selective EGFR TKI epitinib (HMPL-813) in patients with advanced solid tumors and preliminary clinical efficacy in EGFRm+ NSCLC patients with brain metastasis. Journal of Clinical Oncology 2016 34:15_suppl, e20502-e20502

[2]. Zhou et al. Phase I study of the safety and pharmacokinetics of epitinib, an oral EGFR tyrosine kinase inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology 2013 31:15_suppl, e19042-e19042

 Chemical & Physical Properties

Molecular Formula C28H32N6O6
Molecular Weight 548.59
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