Pomalidomide 4'-PEG2-azide

Modify Date: 2024-01-12 21:10:21

Pomalidomide 4'-PEG2-azide Structure
Pomalidomide 4'-PEG2-azide structure
Common Name Pomalidomide 4'-PEG2-azide
CAS Number 2271036-45-2 Molecular Weight 430.41
Density N/A Boiling Point N/A
Molecular Formula C19H22N6O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide 4'-PEG2-azide


Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].

 Names

Name Pomalidomide 4'-PEG2-azide

 Pomalidomide 4'-PEG2-azide Biological Activity

Description Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H22N6O6
Molecular Weight 430.41

 Safety Information

Hazard Codes Xi
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