RTS-V5

Modify Date: 2024-01-06 18:15:00

RTS-V5 Structure
RTS-V5 structure
Common Name RTS-V5
CAS Number 2285346-31-6 Molecular Weight 525.60
Density N/A Boiling Point N/A
Molecular Formula C27H35N5O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RTS-V5


RTS-V5 is a dual HDAC/proteasome inhibitor with IC50s of 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively.

 Names

Name RTS-V5

 RTS-V5 Biological Activity

Description RTS-V5 is a dual HDAC/proteasome inhibitor with IC50s of 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively.
Related Catalog
Target

IC50: 6.9 nM (HDAC1), 18 nM (HDAC2), 15 nM (HDAC3), 0.27 nM (HDAC6), 0.53 nM (HDAC8)[1]

References

[1]. Bhatia S, et al. Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. J Med Chem. 2018 Nov 21;61(22):10299-10309.

 Chemical & Physical Properties

Molecular Formula C27H35N5O6
Molecular Weight 525.60