Top1 inhibitor 1

Modify Date: 2025-08-25 21:04:14

Top1 inhibitor 1 structure	Common Name	Top1 inhibitor 1
	CAS Number	2302772-05-8	Molecular Weight	426.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₂N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Top1 inhibitor 1

Top1 inhibitor 1 (compound 28) is a potent human topoisomerase I (Top1) inhibitor with an IC50 value of 29 nM[1].

Name	Top1 inhibitor 1

Description	Top1 inhibitor 1 (compound 28) is a potent human topoisomerase I (Top1) inhibitor with an IC50 value of 29 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	IC50: 29 nM (human topoisomerase I)[1]
In Vitro	Top1 inhibitor 1 reveals cytotoxicity in cancerous cells including MCF7 (IC50: 2.74 µM), HeLa (IC50: 2.61 µM), HCT116 (IC50: 2.34 µM), NIH: OVCAR-3 (IC50: 2.35 µM) cells compared to the non-cancerous cells like HEK293 (IC50: 8.34 µM) [1].
References	[1]. Kundu B, et al. Discovery and Mechanistic Study of Tailor-Made Quinoline Derivatives as Topoisomerase 1 Poison with Potent Anticancer Activity. J Med Chem. 2019 Apr 11; 62(7):3428-3446.

Molecular Formula	C₂₄H₂₂N₆O₂
Molecular Weight	426.47

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Top1 inhibitor 1
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

Top1 inhibitor 1 suppliers

Top1 inhibitor 1 price