Diketone-PEG4-Biotin

Modify Date: 2024-01-02 17:22:51

Diketone-PEG4-Biotin Structure
Diketone-PEG4-Biotin structure
Common Name Diketone-PEG4-Biotin
CAS Number 2353409-85-3 Molecular Weight 678.84
Density N/A Boiling Point N/A
Molecular Formula C33H50N4O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diketone-PEG4-Biotin


Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diketone-PEG4-Biotin

 Diketone-PEG4-Biotin Biological Activity

Description Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C33H50N4O9S
Molecular Weight 678.84