(S,R,S)-AHPC-C3-NH2

Modify Date: 2024-01-22 16:43:04

(S,R,S)-AHPC-C3-NH2 Structure
(S,R,S)-AHPC-C3-NH2 structure
Common Name (S,R,S)-AHPC-C3-NH2
CAS Number 2361119-88-0 Molecular Weight 515.67
Density N/A Boiling Point N/A
Molecular Formula C26H37N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-C3-NH2


(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader[1].

 Names

Name (S,R,S)-AHPC-C3-NH2

 (S,R,S)-AHPC-C3-NH2 Biological Activity

Description (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader[1].
Related Catalog
Target

VHL

References

[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.

 Chemical & Physical Properties

Molecular Formula C26H37N5O4S
Molecular Weight 515.67
Storage condition 2-8°C