BRM/BRG1 ATP Inhibitor-3
Modify Date: 2024-01-17 11:26:39
BRM/BRG1 ATP Inhibitor-3 structure
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Common Name | BRM/BRG1 ATP Inhibitor-3 | ||
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| CAS Number | 2368901-31-7 | Molecular Weight | 503.64 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H25N5O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BRM/BRG1 ATP Inhibitor-3BRM/BRG1 ATP Inhibitor-3 is a BRG1/BRM inhibitor. BRM/BRG1 ATP Inhibitor-3 inhibits BRM and BRG1 with IC50 values of 10.4 nM and 19.3 nM, respectively. BRM/BRG1 ATP Inhibitor-3 can be used for the research of cancers and BAF complex-related disorders[1]. |
| Name | BRM/BRG1 ATP Inhibitor-3 |
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| Description | BRM/BRG1 ATP Inhibitor-3 is a BRG1/BRM inhibitor. BRM/BRG1 ATP Inhibitor-3 inhibits BRM and BRG1 with IC50 values of 10.4 nM and 19.3 nM, respectively. BRM/BRG1 ATP Inhibitor-3 can be used for the research of cancers and BAF complex-related disorders[1]. |
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| Related Catalog | |
| Target |
IC50: 10.4 nM (BRM); 19.3 nM (BRG1)[1]. |
| In Vitro | BRM/BRG1 ATP Inhibitor-3 has inhibitory activity for BRM and BRG1 with IC50 values of 10.4 nM and 19.3 nM, respectively[1]. BRM/BRG1 ATP Inhibitor-3 (0.01-10 μM) has inhibition for cell proliferation in several cancer cell lines[1]. Cell Proliferation Assay[1] Cell Line: Uveal melanoma cell lines (92-1 , MP41 , MP38, MP46), prostate cancer cell lines (LNCAP), lung cancer cell lines (NCI-H1299), and immortalized embryonic kidney lines (HEK293T) Concentration: 0-10 μM Incubation Time: 3 days Result: Inhibited cell proliferation of uveal melanoma cell line 92-1 and MP41. |
| References |
[1]. Kevin J. Wilson, et al. Compounds and uses thereof. Patent. WO2021155320A1. |
| Molecular Formula | C26H25N5O2S2 |
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| Molecular Weight | 503.64 |