(2E)-3-(4-Ethoxyphenyl)acrylic acid

Modify Date: 2025-08-25 18:48:11

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure
(2E)-3-(4-Ethoxyphenyl)acrylic acid structure
Common Name (2E)-3-(4-Ethoxyphenyl)acrylic acid
CAS Number 2373-79-7 Molecular Weight 192.211
Density 1.2±0.1 g/cm3 Boiling Point 353.2±17.0 °C at 760 mmHg
Molecular Formula C11H12O3 Melting Point 195-199 °C(lit.)
MSDS USA Flash Point 139.2±14.4 °C

 Names

Name 4-ethoxycinnamic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 353.2±17.0 °C at 760 mmHg
Melting Point 195-199 °C(lit.)
Molecular Formula C11H12O3
Molecular Weight 192.211
Flash Point 139.2±14.4 °C
Exact Mass 192.078644
PSA 46.53000
LogP 2.89
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.579

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S36/37/39-S22
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918990090

 Synthetic Route

~99%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Jung, Kwan-Young; Samadani, Ramin; Chauhan, Jay; Nevels, Kerrick; Yap, Jeremy L.; Zhang, Jun; Worlikar, Shilpa; Lanning, Maryanna E.; Chen, Lijia; Ensey, Mary; Shukla, Sagar; Salmo, Rosene; Heinzl, Geoffrey; Gordon, Caryn; Dukes, Troy; MacKerell Jr., Alexander D.; Shapiro, Paul; Fletcher, Steven Organic and Biomolecular Chemistry, 2013 , vol. 11, # 22 p. 3706 - 3732

~90%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Mohite, Amar R.; Bhat, Ramakrishna G. Organic Letters, 2013 , vol. 15, # 17 p. 4564 - 4567

~99%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: De, Prithwiraj; Koumba Yoya, Georges; Constant, Patricia; Bedos-Belval, Florence; Duran, Hubert; Saffon, Nathalie; Daffe, Mamadou; Baltas, Michel Journal of Medicinal Chemistry, 2011 , vol. 54, # 5 p. 1449 - 1461

~%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Organic Letters, , vol. 15, # 17 p. 4564 - 4567

~%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Journal of the Chemical Society, , p. 1467,1469

~%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1449 - 1461

~%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 5 p. 1449 - 1461

~%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Chemische Berichte, , vol. 61, p. 2328

~%

(2E)-3-(4-Ethoxyphenyl)acrylic acid Structure

(2E)-3-(4-Ethox...

CAS#:2373-79-7

Literature: Molecular Crystals and Liquid Crystals, , vol. 577, # 1 p. 36 - 43

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles2

More Articles
Antimalarials. Synthesis and antimalarial activity of 1-(4-methoxycinnamoyl)-4-(5-phenyl-4-oxo-2-oxazolin-2-yl)piperazine and derivatives.

J. Med. Chem. 18(12) , 1216-23, (1975)

The preparation and activity against Plasmodium berghei of derivatives of 1-(4-methoxycinnamoyl)-4-(5-phenyl-4-oxo-2-oxazolin-2-yl)piperazine are described. Replacement of the cinnamoyl group was acco...

Cholest-5-en-3ß-yl 3-(4-ethoxyphenyl) prop-2-enoate. Bugenhagen B, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 68(7) , o2064-o2064, (2012)

 Synonyms

3-(4-ETHOXYPHENYL)ACRYLIC ACID
(2E)-3-(4-ethoxyphenyl)prop-2-enoic acid
(E)-3-(4-ethoxyphenyl)acrylic acid
P-ETHOXYCINNAMIC ACID
(E)-4-ethoxycinnamic acid
4-ETHOXYPHENYLACRYLIC ACID
4-ethoxy-trans-cinnamic acid
4-Ethoxycinnanic acid
MFCD00016848
(2E)-3-(4-Ethoxyphenyl)acrylic acid
2-Propenoic acid, 3-(4-ethoxyphenyl)-, (2E)-
(E)-3-(4-ethoxyphenyl)prop-2-enoic acid
3-(4-ethoxyphenyl)-2-propenoic acid
AURORA 6885
4-Ethoxyciamic acid
4-EthoxycinnaMic Acid
RARECHEM BK HW 0106
4-Ethoxy cinnamic acid
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