PD-1/PD-L1-IN 6
Modify Date: 2024-01-06 11:24:04
PD-1/PD-L1-IN 6 structure
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Common Name | PD-1/PD-L1-IN 6 | ||
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| CAS Number | 2393983-76-9 | Molecular Weight | 402.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H26N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PD-1/PD-L1-IN 6PD-1/PD-L1-IN 6 (compound A13) is a potent PD-1/PD-L1 interaction inhibitor, with an IC50 of 132.8 nM. PD-1/PD-L1-IN 6 exhibits outstanding immunoregulatory activity. PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion in a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, without significant toxic effect. PD-1/PD-L1-IN 6 restores the immune response in a T cell-tumor co-culture model[1]. |
| Name | PD-1/PD-L1-IN 6 |
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| Description | PD-1/PD-L1-IN 6 (compound A13) is a potent PD-1/PD-L1 interaction inhibitor, with an IC50 of 132.8 nM. PD-1/PD-L1-IN 6 exhibits outstanding immunoregulatory activity. PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion in a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, without significant toxic effect. PD-1/PD-L1-IN 6 restores the immune response in a T cell-tumor co-culture model[1]. |
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| Related Catalog | |
| Target |
IC50: 132.8 ± 6.9 nM (PD-1/PD-L1 interaction) |
| References |
| Molecular Formula | C25H26N2O3 |
|---|---|
| Molecular Weight | 402.49 |