HDAC3/6-IN-2 structure
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Common Name | HDAC3/6-IN-2 | ||
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CAS Number | 2417510-17-7 | Molecular Weight | 822.09 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C49H67N5O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of HDAC3/6-IN-2HDAC3/6-IN-2 (compound 15) is a potent HDAC6 and HDAC3 inhibitor, with IC50 values of 0.368 and 0.635 μM, respectively. HDAC3/6-IN-2 shows antitumor activity, and induces cancer cell apoptosis. HDAC3/6-IN-2 decreases the levels of HDAC6 and HDAC3, associated with upregulation of acetylated H3 and α-tubulin[1]. |
Name | HDAC3/6-IN-2 |
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Description | HDAC3/6-IN-2 (compound 15) is a potent HDAC6 and HDAC3 inhibitor, with IC50 values of 0.368 and 0.635 μM, respectively. HDAC3/6-IN-2 shows antitumor activity, and induces cancer cell apoptosis. HDAC3/6-IN-2 decreases the levels of HDAC6 and HDAC3, associated with upregulation of acetylated H3 and α-tubulin[1]. |
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Related Catalog | |
Target |
HDAC6:0.368 μM (IC50) HDAC3:0.635 μM (IC50) HDAC1:2.512 μM (IC50) HDAC2:4.830 μM (IC50) |
References |
Molecular Formula | C49H67N5O6 |
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Molecular Weight | 822.09 |