GLUT inhibitor-1
Modify Date: 2024-01-02 20:18:43
GLUT inhibitor-1 structure
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Common Name | GLUT inhibitor-1 | ||
|---|---|---|---|---|
| CAS Number | 2421141-40-2 | Molecular Weight | 549.67 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H35N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GLUT inhibitor-1GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases[1]. |
| Name | GLUT inhibitor-1 |
|---|
| Description | GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases[1]. |
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| Related Catalog | |
| Target |
GLUT1:242 nM (IC50) GLUT3:179 nM (IC50) |
| In Vivo | Summary of the pharmacokinetic parameters of GLUT inhibitor-1 (compound 15b; 30 mg/kg) in mouse and rat[1]. Parameter Mouse Rat oral Cmax (ng/mL) 2525 1675 oral AUC (ng/mL) 5890 6813 CL (mL/min/kg) 40 37 Vdss (L/Kg) 1.70 4.51 t1/2 (h) 0.785 2.59 F (%) 45.4 49.4 B/Pb 0.05 b: Solubility is determined in PBS buffer solutions. |
| References |
| Molecular Formula | C32H35N7O2 |
|---|---|
| Molecular Weight | 549.67 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: GLUTinhibitor-1
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tom
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: GLUT inhibitor-1
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: GLUT inhibitor-1
- Price: ￥750.0/100mg ￥1400.0/250mg ￥2900.0/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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