VEGFR-2-IN-21

Modify Date: 2024-04-09 19:49:16

VEGFR-2-IN-21 structure	Common Name	VEGFR-2-IN-21
	CAS Number	2531029-88-4	Molecular Weight	574.05
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₄ClN₇O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VEGFR-2-IN-21

VEGFR-2-IN-21 (Compound 5d) is a potent VEGFR-2 inhibitor with an IC50 of 0.10 μM. VEGFR-2-IN-21 shows anticancer activity[1].

Name	VEGFR-2-IN-21

Description	VEGFR-2-IN-21 (Compound 5d) is a potent VEGFR-2 inhibitor with an IC50 of 0.10 μM. VEGFR-2-IN-21 shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR-2:0.10 μM (IC50)
In Vitro	VEGFR-2-IN-21 (Compound 5d) shows inhibitory activities against the three HepG2, HCT116 and MCF-7 cancer cell lines with IC50 values of 8.98 ± 0.1, 7.77 ± 0.1 and 6.99 ± 0.1 µM respectively[1].
References	[1]. Saleh NM, et al. Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors. Bioorg Chem. 2020 Nov;104:104350.

Molecular Formula	C₂₈H₂₄ClN₇O₃S
Molecular Weight	574.05