EGFR-IN-56

Modify Date: 2025-08-31 02:11:48

EGFR-IN-56 structure	Common Name	EGFR-IN-56
	CAS Number	2477726-83-1	Molecular Weight	434.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₂N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-56

EGFR-IN-56 (Compound 13a) is a potent EGFR inhibitor with IC50 values of 541.7 nM and 132.1 nM against EGFRT790M and EGFRT790M/L858R, respectively. EGFR-IN-56 blocks cancer cells in G2/M phase and induce into late apoptosis[1].

Name	EGFR-IN-56

Description	EGFR-IN-56 (Compound 13a) is a potent EGFR inhibitor with IC50 values of 541.7 nM and 132.1 nM against EGFRT790M and EGFRT790M/L858R, respectively. EGFR-IN-56 blocks cancer cells in G2/M phase and induce into late apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFRT790M:541.7 nM (IC50) EGFRL858R/T790M:132.1 nM (IC50)
References	[1]. Xiao Z, et al. Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115669.

Molecular Formula	C₂₃H₂₂N₄O₃S
Molecular Weight	434.51

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EGFR-IN-56

Use of EGFR-IN-56

Names

EGFR-IN-56 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.