PAR-3 (1-6) amide (mouse) trifluoroacetate salt
Modify Date: 2025-08-25 15:56:26
PAR-3 (1-6) amide (mouse) trifluoroacetate salt structure
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Common Name | PAR-3 (1-6) amide (mouse) trifluoroacetate salt | ||
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| CAS Number | 261521-21-5 | Molecular Weight | 576.60 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1229.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C25H36N8O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 697.4±34.3 °C | |
Use of PAR-3 (1-6) amide (mouse) trifluoroacetate saltSFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.) |
| Name | L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide |
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| Synonym | More Synonyms |
| Description | SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.) |
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| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1229.5±65.0 °C at 760 mmHg |
| Molecular Formula | C25H36N8O8 |
| Molecular Weight | 576.60 |
| Flash Point | 697.4±34.3 °C |
| Exact Mass | 576.265625 |
| LogP | -2.38 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.602 |
| L-Seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide |
| L-Prolinamide, L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl- |
| SFNGGP-NH2 PAR3 Tethered Ligand (Murine) / Activates PAR1 and PAR2 |
| PAR-3 (1-6) amide (mouse) |