RET-IN-12

Modify Date: 2025-10-14 11:17:50

RET-IN-12 Structure
RET-IN-12 structure
Common Name RET-IN-12
CAS Number 2684252-55-7 Molecular Weight 581.59
Density N/A Boiling Point N/A
Molecular Formula C30H30F3N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RET-IN-12


RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively[1].

 Names

Name RET-IN-12

 RET-IN-12 Biological Activity

Description RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively[1].
Related Catalog
References

[1]. ZHANG YANG (CN), et al. PHENYL BISAMIDE COMPOUND. Patent WO2021164741A1.

 Chemical & Physical Properties

Molecular Formula C30H30F3N5O4
Molecular Weight 581.59
InChIKey QKFNPAFXWLCCMF-UHFFFAOYSA-N
SMILES COc1cc2cc(-c3ccc(CC(=O)Nc4cc(C(=O)NCCN(C)C)cc(C(F)(F)F)c4)cn3)cnc2cc1OC
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