Taurodeoxycholate-d6 sodium salt

Modify Date: 2023-05-20 11:33:50

Taurodeoxycholate-d6 sodium salt structure	Common Name	Taurodeoxycholate-d6 sodium salt
	CAS Number	2687960-92-3	Molecular Weight	528.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₉D₆NNaO₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Taurodeoxycholate-d6 sodium salt

Taurodeoxycholate-d6 (sodium salt) is the deuterium labeled Taurodeoxycholate sodium salt[1]. Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[2]. [2][3].

Name	Taurodeoxycholate-d6 sodium salt

Description	Taurodeoxycholate-d6 (sodium salt) is the deuterium labeled Taurodeoxycholate sodium salt[1]. Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[2]. [2][3].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13. [3]. Kispal G,et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25261(30):14209-13. [4]. Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2019 Jun 19:1-9.

Molecular Formula	C₂₆H₃₉D₆NNaO₆S
Molecular Weight	528.73

Taurodeoxycholate-d6 sodium salt

Use of Taurodeoxycholate-d6 sodium salt

Names

Taurodeoxycholate-d6 sodium salt Biological Activity

Chemical & Physical Properties