JNJ-4355 structure
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Common Name | JNJ-4355 | ||
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CAS Number | 2697112-32-4 | Molecular Weight | 760.32 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C40H43ClFN5O5S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of JNJ-4355JNJ-4355 is a highly potent MCL-1 (myeloid cell leukemia-1) inhibitor, with KI of 18 pM. JNJ-4355 shows antitumor activity[1][2]. |
Name | JNJ-4355 |
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Description | JNJ-4355 is a highly potent MCL-1 (myeloid cell leukemia-1) inhibitor, with KI of 18 pM. JNJ-4355 shows antitumor activity[1][2]. |
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Related Catalog | |
Target |
Mcl-1:18 pM (Ki) |
In Vitro | JNJ-4355 shows promising in vitro potency data in cancer cell lines and AML patient-derived samples[2]. |
In Vivo | JNJ-4355 (IV , single) shows complete tumor regression in a mouse MOLP8 (multiple myeloma) xenograft[2]. |
References |
Molecular Formula | C40H43ClFN5O5S |
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Molecular Weight | 760.32 |