Thalidomide-PEG5-NH2 hydrochloride
Modify Date: 2025-09-21 19:50:37
Thalidomide-PEG5-NH2 hydrochloride structure
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Common Name | Thalidomide-PEG5-NH2 hydrochloride | ||
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| CAS Number | 2703775-06-6 | Molecular Weight | 529.97 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H32ClN3O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-PEG5-NH2 hydrochlorideThalidomide-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-PEG5-NH2 hydrochloride |
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| Description | Thalidomide-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTAC 包含两个不同的配体，通过一个接头连接；一个是 E3 泛素连接酶的配体，另一个是靶蛋白的配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白[2]。 |
| References |
| Molecular Formula | C23H32ClN3O9 |
|---|---|
| Molecular Weight | 529.97 |