Thalidomide-NH-PEG1-NH2 hydrochloride
Modify Date: 2023-01-16 12:41:35
Thalidomide-NH-PEG1-NH2 hydrochloride structure
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Common Name | Thalidomide-NH-PEG1-NH2 hydrochloride | ||
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| CAS Number | 2154342-56-8 | Molecular Weight | 396.83 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H21ClN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-PEG1-NH2 hydrochlorideThalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-NH-PEG1-NH2 hydrochloride |
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| Description | Thalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C17H21ClN4O5 |
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| Molecular Weight | 396.83 |
| Hazard Codes | Xi |
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