PROTAC IRAK3 degrade-1

Modify Date: 2025-08-26 22:59:57

PROTAC IRAK3 degrade-1 Structure
PROTAC IRAK3 degrade-1 structure
Common Name PROTAC IRAK3 degrade-1
CAS Number 2712600-00-3 Molecular Weight 878.07
Density N/A Boiling Point N/A
Molecular Formula C47H63N11O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC IRAK3 degrade-1


PROTAC IRAK3 degrade-1 is a potent and selective degrader of IRAK3 (IC50 = 5 nM).

 Names

Name PROTAC IRAK3 degrade-1

 PROTAC IRAK3 degrade-1 Biological Activity

Description PROTAC IRAK3 degrade-1 is a potent and selective degrader of IRAK3 (IC50 = 5 nM).
Related Catalog
References

[1]. Degorce SL, et al. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase. J Med Chem. 2020 Sep 24;63(18):10460-10473.

 Chemical & Physical Properties

Molecular Formula C47H63N11O6
Molecular Weight 878.07
InChIKey ZUODKONSNNHSAJ-UHFFFAOYSA-N
SMILES CC(C)c1ccn2ncnc(NC3CCC(N4CCN(C(=O)CCC(=O)N5CCC(CCN6CCN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)CC5)CC4)CC3)c12
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