QH536

Modify Date: 2024-01-15 22:43:26

QH536 structure	Common Name	QH536
	CAS Number	2754254-07-2	Molecular Weight	535.76
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₄₉N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of QH536

QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research[1].

Name	QH536

Description	QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR) Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	IC50: 0.22 μM (HMGCR)[1]
References	[1]. Li XZ, et al. Synthesis of heterocyclic ring-fused analogs of HMG499 as novel degraders of HMG-CoA reductase that lower cholesterol. Eur J Med Chem. 2022 Jun 5;236:114323.

Molecular Formula	C₃₃H₄₉N₃O₃
Molecular Weight	535.76

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: QH536
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: QH536
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

QH536 suppliers

QH536 price

QH536

Use of QH536

Names

QH536 Biological Activity

Chemical & Physical Properties