3-Nitrocoumarin

Modify Date: 2024-01-08 20:53:07

3-Nitrocoumarin Structure
3-Nitrocoumarin structure
Common Name 3-Nitrocoumarin
CAS Number 28448-04-6 Molecular Weight 191.14
Density N/A Boiling Point N/A
Molecular Formula C9H5NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-Nitrocoumarin


3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor[1].

 Names

Name 3-nitrochromen-2-one
Synonym More Synonyms

 3-Nitrocoumarin Biological Activity

Description 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor[1].
Related Catalog
Target

PLC-γ[1].

References

[1]. Ward PD, et al. Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. J Biol Chem. 2002 Sep 20;277(38):35760-5.

 Chemical & Physical Properties

Molecular Formula C9H5NO4
Molecular Weight 191.14
Exact Mass 191.02200
PSA 76.03000
LogP 2.22440

 Safety Information

Hazard Codes Xi

 Synonyms

3-nitro-chromen-2-one
3-nitro-2H-chromen-2-one
3-nitrocoumarin
HMS545H12