7-Nitroindazole structure
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Common Name | 7-Nitroindazole | ||
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CAS Number | 2942-42-9 | Molecular Weight | 163.133 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 211.2±23.0 °C at 760 mmHg | |
Molecular Formula | C7H5N3O2 | Melting Point | 185-186°C | |
MSDS | Chinese USA | Flash Point | 81.5±22.6 °C | |
Symbol |
GHS06, GHS08 |
Signal Word | Danger |
Use of 7-Nitroindazole7-Nitroindazole is a selective nNOS inhibitor with antinociceptive and cardiovascular effects. 7-Nitroindazole is a useful tool to evaluate the biological roles of nitric oxide in the central nervous system[1][2]. |
Name | 7-nitro-1H-indazole |
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Synonym | More Synonyms |
Description | 7-Nitroindazole is a selective nNOS inhibitor with antinociceptive and cardiovascular effects. 7-Nitroindazole is a useful tool to evaluate the biological roles of nitric oxide in the central nervous system[1][2]. |
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Related Catalog | |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 211.2±23.0 °C at 760 mmHg |
Melting Point | 185-186°C |
Molecular Formula | C7H5N3O2 |
Molecular Weight | 163.133 |
Flash Point | 81.5±22.6 °C |
Exact Mass | 163.038177 |
PSA | 74.50000 |
LogP | 1.42 |
Vapour Pressure | 0.2±0.4 mmHg at 25°C |
Index of Refraction | 1.741 |
Storage condition | −20°C |
Water Solubility | slightly soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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Symbol |
GHS06, GHS08 |
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Signal Word | Danger |
Hazard Statements | H301-H319-H351-H360 |
Precautionary Statements | P201-P281-P301 + P310-P305 + P351 + P338-P308 + P313 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | T:Toxic; |
Risk Phrases | R60;R40 |
Safety Phrases | S53-S22-S36/37/39-S45 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | NK7962200 |
Hazard Class | 6.1 |
HS Code | 2933990090 |
~97% 7-Nitroindazole CAS#:2942-42-9 |
Literature: GRUeNENTHAL GMBH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; SCHIENE, Klaus; DE VRY, Jean; DAMANN, Nils; FRORMANN, Sven; LESCH, Bernhard; LEE, Jeewoo; KIM, Yong-Soo; KIM, Myeong-Seop Patent: WO2010/127855 A1, 2010 ; Location in patent: Page/Page column 124; 125 ; |
~98% 7-Nitroindazole CAS#:2942-42-9 |
Literature: El Kazzouli, Said; Koubachi, Jamal; Berteina-Raboin, Sabine; Mouaddib, Abderrahim; Guillaumet, Gerald Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8575 - 8577 |
~76% 7-Nitroindazole CAS#:2942-42-9 |
Literature: Lokhande; Raheem, Abdul; Sabale; Chabukswar; Jagdale Tetrahedron Letters, 2007 , vol. 48, # 39 p. 6890 - 6892 |
Precursor 3 | |
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DownStream 10 | |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Neuropharmacology 89 , 87-99, (2014) It is well known that nitric oxide (NO) interacts with dopamine (DA) within the striatal circuitry. The anti-dyskinetic properties of NO synthase (NOS) inhibitors demonstrate the importance of NO in L... |
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1H-Indazole,7-nitro |
MFCD00022789 |
nitro-7 indazole |
7-Nitroindazole |
7-NI |
2H-Indazole, 7-nitro- |
7-Nitro-1H-indazole |
7-Nitro-2H-indazole |
EINECS 220-934-4 |