GSA-10 structure
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Common Name | GSA-10 | ||
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CAS Number | 300833-95-8 | Molecular Weight | 450.527 | |
Density | 1.240±0.06 g/cm3 | Boiling Point | 620.2±55.0 °C at 760 mmHg | |
Molecular Formula | C26H30N2O5 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 328.9±31.5 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of GSA-10GSA-10 is a potent agonist of Smoothened (Smo) receptor with an EC50 of 1.2 μM. GSA-10 is a novel quinolinecarboxamide derivative. GSA-10 acts at Smo to promote the differentiation of multipotent mesenchymal progenitor cells into osteoblasts. GSA-10 mediates Hedgehog (Hh) signaling which may have researching interests in regenerative medicine for cancer disease[1][2]. |
Name | propyl 4-(1-hexyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)benzoate |
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Synonym | More Synonyms |
Description | GSA-10 is a potent agonist of Smoothened (Smo) receptor with an EC50 of 1.2 μM. GSA-10 is a novel quinolinecarboxamide derivative. GSA-10 acts at Smo to promote the differentiation of multipotent mesenchymal progenitor cells into osteoblasts. GSA-10 mediates Hedgehog (Hh) signaling which may have researching interests in regenerative medicine for cancer disease[1][2]. |
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Related Catalog | |
Target |
Smoothened receptor[1] |
References |
Density | 1.240±0.06 g/cm3 |
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Boiling Point | 620.2±55.0 °C at 760 mmHg |
Molecular Formula | C26H30N2O5 |
Molecular Weight | 450.527 |
Flash Point | 328.9±31.5 °C |
Exact Mass | 450.215485 |
PSA | 97.63000 |
LogP | 5.79 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.610 |
Water Solubility | Insuluble (4.1E-4 g/L) (25 ºC) |
Propyl 4-{[(1-hexyl-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl)carbonyl]amino}benzoate |
Benzoic acid, 4-[[(1-hexyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl]amino]-, propyl ester |
propyl 4-{[(1-hexyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)carbonyl]amino}benzoate |
GSA 10 |
4-[[(1-Hexyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl]amino]benzoic acid propyl ester |