WAY 170523
Modify Date: 2024-01-24 15:58:36
WAY 170523 structure
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Common Name | WAY 170523 | ||
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| CAS Number | 307002-73-9 | Molecular Weight | 613.68 | |
| Density | 1.352g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C33H31N3O7S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of WAY 170523WAY-170523 is a potent and selective MMP-13 (matrix metalloproteinase-13) inhibitor, with an IC50 of 17 nM. WAY-170523 can directly attenuate ERK1/2 phosphorylation. WAY-170523 inhibits the invasion of PC-3 cells, can be used for prostate cancer research[1][2]. |
| Name | WAY 170523,N-[2-[4-[[[2-[(Hydroxyamino)carbonyl]-4,6-dimethylphenyl](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]-2-benzofurancarboxamide |
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| Description | WAY-170523 is a potent and selective MMP-13 (matrix metalloproteinase-13) inhibitor, with an IC50 of 17 nM. WAY-170523 can directly attenuate ERK1/2 phosphorylation. WAY-170523 inhibits the invasion of PC-3 cells, can be used for prostate cancer research[1][2]. |
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| Related Catalog | |
| Target |
MMP13:17 nM (IC50) MMP-1:10 μM (IC50) MMP-9:945 nM (IC50) |
| In Vitro | WAY-170523 has an IC50 of 17 nM for MMP-13 and shows > 5800-, 56-, and > 500-fold selectivity against MMP-I, MMP-9, and TACE, respectively. |
| References |
| Density | 1.352g/cm3 |
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| Molecular Formula | C33H31N3O7S |
| Molecular Weight | 613.68 |
| Exact Mass | 613.18800 |
| PSA | 146.56000 |
| LogP | 7.23550 |
| Index of Refraction | 1.656 |
| RIDADR | NONH for all modes of transport |
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