WNK1-IN-1
Modify Date: 2024-01-14 10:28:31
WNK1-IN-1 structure
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Common Name | WNK1-IN-1 | ||
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| CAS Number | 324022-39-1 | Molecular Weight | 446.14 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H15BrCl2N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of WNK1-IN-1WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1]. |
| Name | WNK1-IN-1 |
|---|
| Description | WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 1.6 μM (WNK1), 4.3 μM (OSR1 phosphorylation)[1] |
| In Vitro | WNK1-IN-1 (0-1000 μM; 30 min) shows high potency to WNK1 with an IC50 value of 1.6 μM[1]. WNK1-IN-1 (0.2-12.5 μM; 24 h) inhibits endogenous OSR1 phosphorylation with an IC50 value of 4.3 μM in MDAMB231 breast-cancer cells[1]. WNK1-IN-1 (0-100 mM) is 10-fold more potent to WNK1 than WNK3 in Kinase-Glo assay[1]. |
| Molecular Formula | C13H15BrCl2N2O4S |
|---|---|
| Molecular Weight | 446.14 |