WNK1-IN-1

Modify Date: 2024-01-14 10:28:31

WNK1-IN-1 structure	Common Name	WNK1-IN-1
	CAS Number	324022-39-1	Molecular Weight	446.14
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₅BrCl₂N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of WNK1-IN-1

WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1].

Name	WNK1-IN-1

Description	WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cancer Research Areas >> Cardiovascular Disease
Target	IC50: 1.6 μM (WNK1), 4.3 μM (OSR1 phosphorylation)[1]
In Vitro	WNK1-IN-1 (0-1000 μM; 30 min) shows high potency to WNK1 with an IC50 value of 1.6 μM[1]. WNK1-IN-1 (0.2-12.5 μM; 24 h) inhibits endogenous OSR1 phosphorylation with an IC50 value of 4.3 μM in MDAMB231 breast-cancer cells[1]. WNK1-IN-1 (0-100 mM) is 10-fold more potent to WNK1 than WNK3 in Kinase-Glo assay[1].

Molecular Formula	C₁₃H₁₅BrCl₂N₂O₄S
Molecular Weight	446.14

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: WNK1-IN-1
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
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