2-Aminobenzenesulfonamide
2-Aminobenzenesulfonamide structure
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Common Name | 2-Aminobenzenesulfonamide | ||
|---|---|---|---|---|
| CAS Number | 3306-62-5 | Molecular Weight | 172.205 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 392.7±44.0 °C at 760 mmHg | |
| Molecular Formula | C6H8N2O2S | Melting Point | 155-157 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 191.3±28.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 2-Aminobenzenesulfonamide2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor. |
Summary: 2-Aminobenzenesulfonamide, also known as 2-aminobenzenesulfonamide, CAS number 3306-62-5, with molecular formula C6H8N2O2S and molecular weight 172.205. It appears as white to off-white crystalline powder or crystals, with a melting point of 155-157°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-Aminobenzenesulfonamide |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor. |
|---|---|
| Related Catalog | |
| Target |
carbonic anhydrase IX[1] |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 392.7±44.0 °C at 760 mmHg |
| Melting Point | 155-157 °C(lit.) |
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.205 |
| Flash Point | 191.3±28.4 °C |
| Exact Mass | 172.030655 |
| PSA | 94.56000 |
| LogP | 0.22 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.628 |
| InChIKey | YAZSBRQTAHVVGE-UHFFFAOYSA-N |
| SMILES | Nc1ccccc1S(N)(=O)=O |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S36/37/39-S26-S22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DA9449000 |
| HS Code | 2935009090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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2-Aminobenzenes... CAS#:3306-62-5 |
| Literature: Ismail, Mohamed A.H.; Abou El Ella, Dalal A.; Abouzid, Khaled A.M.; Mahmoud, Amr H. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 17 p. 5647 - 5647 |
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| Literature: US4806640 A1, ; |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 14 p. 3833 - 3838 |
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| Literature: US4976773 A1, ; |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 14 p. 3833 - 3838 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 14 p. 3833 - 3838 |
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 14 p. 3887 - 3890 |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 20, # 7 p. 2455 - 2478 |
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2-Aminobenzenes... CAS#:3306-62-5 |
| Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2> 95, p. 393 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
|---|---|
| DownStream 10 | |
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CAS#:13514-00-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1 moiety.
Bioorg. Med. Chem. 16(6) , 2955-67, (2008) Inhibition of the hepatitis C virus (HCV) NS3 protease has emerged as an attractive approach to defeat the global hepatitis C epidemic. In this work, we present the synthesis and biochemical evaluatio... |
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Nitrogen-15 nuclear magnetic resonance study of benzenesulfonamide and cyanate binding to carbonic anhydrase.
Biochemistry 22 , 2658, (1983)
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Heterocycles with a benzothiadiazepine moiety. 5. Derivatives of pyrrolo[2,1-d][1,2,5]benzothiadiazepine, a novel tricyclic ring.
Il Farmaco 52(6-7) , 375-8, (1997) The synthesis of pyrrolo[2,1-d][1,2,5]benzothiadiazepin-7(6H)-one 5,5-dioxide has been achieved by reaction between 2-(1H-pyrrol-1-yl)benzenesulfonamide and triphosgene. N-Ethylation of the tricyclic ... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-Aminobenzenesulfonamide |
| orthanilamide |
| aminobenzenesulfonamide |
| 2-Sulphamoylaniline |
| EINECS 221-988-1 |
| MFCD08443599 |
| sulfamoylaniline |
| o-sulfanilamide |
| 2-amino-benzenesulfonamid |
| o-amino-benzenesulfonamid |
| 2-Aminobenzenesulfonamde |
| 2-Amino-Benzensulfonamide |
| o-aminobenzenesulfonamide |
| 2-Aminobenzenesulfamide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of 2-Aminobenzenesulfonamide? |
| A: Melting point of 2-Aminobenzenesulfonamide is 155-157 °C(lit.). |
| Q: What is the English name of 2-Aminobenzenesulfonamide? |
| A: The English name of 2-Aminobenzenesulfonamide is 2-Aminobenzenesulfonamide. |
| Q: What is the safety information for 2-Aminobenzenesulfonamide? |
| A: Safety information for 2-Aminobenzenesulfonamide: S36/37/39-S26-S22. |
| Q: What is the molecular formula of 2-Aminobenzenesulfonamide? |
| A: Molecular formula of 2-Aminobenzenesulfonamide is C6H8N2O2S. |
| Q: What is the polar surface area (PSA) of 2-Aminobenzenesulfonamide? |
| A: Polar surface area (PSA) of 2-Aminobenzenesulfonamide is 94.56000. |
| Q: What are the uses of 2-Aminobenzenesulfonamide? |
| A: Main uses of 2-Aminobenzenesulfonamide: 2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor. |
| Q: What is the SMILES notation of 2-Aminobenzenesulfonamide? |
| A: SMILES notation of 2-Aminobenzenesulfonamide is Nc1ccccc1S(N)(=O)=O. |
| Q: What is the LogP of 2-Aminobenzenesulfonamide? |
| A: LogP of 2-Aminobenzenesulfonamide is 0.22. |
| Q: What is the boiling point of 2-Aminobenzenesulfonamide? |
| A: Boiling point of 2-Aminobenzenesulfonamide is 392.7±44.0 °C at 760 mmHg. |
| Q: What are the upstream materials of 2-Aminobenzenesulfonamide? |
| A: Related upstream materials(CAS) of 2-Aminobenzenesulfonamide: 5455-59-4;107342-23-4;13338-00-6;1694-92-4;121-51-7;50881-48-6;6961-82-6. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |