Aurora Kinase Inhibitor II
Modify Date: 2024-01-08 17:39:00
Aurora Kinase Inhibitor II structure
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Common Name | Aurora Kinase Inhibitor II | ||
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| CAS Number | 331770-21-9 | Molecular Weight | 400.43000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H20N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aurora Kinase Inhibitor IIAurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively[1]. |
| Name | N-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively[1]. |
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| Related Catalog | |
| Target |
Aurora A:310 nM (IC50) Aurora B:240 nM (IC50) |
| In Vitro | Aurora kinase inhibitor-2 (Compound 1) shows excellent levels of Aurora A enzyme inhibition and is also effective in an MCF7 cellular anti-proliferative assay (IC50 value of 1.25 µM)[2]. |
| References |
| Molecular Formula | C23H20N4O3 |
|---|---|
| Molecular Weight | 400.43000 |
| Exact Mass | 400.15400 |
| PSA | 85.37000 |
| LogP | 4.78890 |
| quinazoline deriv. 1 |
| Aurora Kinase Inhibitor II |
| 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline |
| Anilinoquinazoline1 |