FTI-2153

Modify Date: 2024-01-19 23:45:11

FTI-2153 structure	Common Name	FTI-2153
	CAS Number	344900-92-1	Molecular Weight	466.59600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₀N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FTI-2153

FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].

Name	fti-2153

Description	FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Sun J, et al. Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine. Cancer Res. 1999 Oct 1;59(19):4919-26.

Molecular Formula	C₂₅H₃₀N₄O₃S
Molecular Weight	466.59600
Exact Mass	466.20400
PSA	121.41000
LogP	4.48120

Hazard Codes	Xi

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FTI-2153
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Purity: 98.0%
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Contact: Yang
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