Caloxin 2A1 trifluoroacetate salt

Modify Date: 2024-01-09 11:36:12

Caloxin 2A1 trifluoroacetate salt structure	Common Name	Caloxin 2A1 trifluoroacetate salt
	CAS Number	350670-85-8	Molecular Weight	1478.521
	Density	1.4±0.1 g/cm3	Boiling Point	2095.7±65.0 °C at 760 mmHg
	Molecular Formula	C₆₄H₉₁N₁₉O₂₂	Melting Point	N/A
	MSDS	N/A	Flash Point	1221.3±34.3 °C

Use of Caloxin 2A1 trifluoroacetate salt

Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].

Name	L-Valyl-L-seryl-L-asparaginyl-L-seryl-L-asparaginyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-serylglycylglycylglycinamide
Synonym	More Synonyms

Description	Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump
In Vitro	Caloxin 2A1 inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate[1]. Caloxin 2A1 increases airway smooth muscle cells (ASMCs) apoptosis[2].
References	[1]. J Chaudhary, et al. Caloxin: a novel plasma membrane Ca2+ pump inhibitor. Am J Physiol Cell Physiol. 2001 Apr;280(4):C1027-30. [2]. Yi-fei Chen, et al. Plasma membrane Ca2+-ATPase regulates Ca2+ signaling and the proliferation of airway smooth muscle cells. Eur J Pharmacol. 2014 Oct 5;740:733-41.

Density	1.4±0.1 g/cm3
Boiling Point	2095.7±65.0 °C at 760 mmHg
Molecular Formula	C₆₄H₉₁N₁₉O₂₂
Molecular Weight	1478.521
Flash Point	1221.3±34.3 °C
Exact Mass	1477.658569
LogP	-4.68
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.625

L-Valyl-L-seryl-L-asparaginyl-L-seryl-L-asparaginyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-serylglycylglycylglycinamide

Glycinamide, L-valyl-L-seryl-L-asparaginyl-L-seryl-L-asparaginyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-serylglycylglycyl-

DC Chemicals Limited
China
Product Name: Caloxin 2A1
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Taiwan Oyi peptide Co. Ltd
China
Product Name: Caloxin 2A1 trifluoroacetate salt
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

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