2-Hydroxy-2-methylbutyric acid

Modify Date: 2024-01-04 17:55:12

2-Hydroxy-2-methylbutyric acid Structure
2-Hydroxy-2-methylbutyric acid structure
Common Name 2-Hydroxy-2-methylbutyric acid
CAS Number 3739-30-8 Molecular Weight 118.131
Density 1.1±0.1 g/cm3 Boiling Point 237.6±13.0 °C at 760 mmHg
Molecular Formula C5H10O3 Melting Point 73-75 °C(lit.)
MSDS Chinese USA Flash Point 111.8±16.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Hydroxy-2-methylbutyric acid


2-Hydroxy-2-methylbutanoic acid, an unusual metabolite, is associated with 2-hydroxyglutaric aciduria and maple syrup urine disease.

 Names

Name 2-hydroxy-2-methylbutyric acid
Synonym More Synonyms

 2-Hydroxy-2-methylbutyric acid Biological Activity

Description 2-Hydroxy-2-methylbutanoic acid, an unusual metabolite, is associated with 2-hydroxyglutaric aciduria and maple syrup urine disease.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Dekant W, et al. Biotransformation of MTBE, ETBE, and TAME after inhalation or ingestion in rats and humans. Res Rep Health Eff Inst. 2001 May;(102):29-71; discussion 95-109.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 237.6±13.0 °C at 760 mmHg
Melting Point 73-75 °C(lit.)
Molecular Formula C5H10O3
Molecular Weight 118.131
Flash Point 111.8±16.3 °C
Exact Mass 118.062996
PSA 57.53000
LogP 0.18
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.460

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918199090

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

2-hydroxy-2-methyl-butyric acid
2-Hydroxy-2-methyl-n-butyric acid
2-Hydroxy-2-methylbutyric acid
EINECS 223-120-7
2-Hydroxy-2-methylbutanoic acid
Butanoic acid, 2-hydroxy-2-methyl-
2-hydroxy-2-methyl-butanoic acid
MFCD00004476