Penicillin G benzathine tetrahydrate

Modify Date: 2025-08-25 21:34:47

Penicillin G benzathine tetrahydrate Structure
Penicillin G benzathine tetrahydrate structure
 Common Name Penicillin G benzathine tetrahydrate
CAS Number 41372-02-5 Molecular Weight 981.185
Density N/A Boiling Point 1299.8ºC at 760 mmHg
Molecular Formula C48H64N6O12S2 Melting Point 123-124°C
MSDS N/A Flash Point 739.9ºC

 Use of Penicillin G benzathine tetrahydrate


Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is an antibiotic against many bacterial infections[1].

 Names

Name N,N'-dibenzylethane-1,2-diamine,(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,tetrahydrate
Synonym More Synonyms

 Penicillin G benzathine tetrahydrate Biological Activity

Description Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is an antibiotic against many bacterial infections[1].
Related Catalog
In Vivo Penicillin G benzathine tetrahydrate displays activity and antibacterial effect in CD-I mice infected with Staphylococcus aureus Smith[2].
References

[1]. Bowen AC, et al. Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial. Lancet. 2014 Dec 13;384(9960):2132-40.

[2]. J A Yurchenco, et al. Substituted Penicillin Amides. Duration of Antibacterial Activity (Depot Effect) in Experimental Infections in Mice. Chemotherapy . 1972;17(6):405-15.

 Chemical & Physical Properties

Boiling Point 1299.8ºC at 760 mmHg
Melting Point 123-124°C
Molecular Formula C48H64N6O12S2
Molecular Weight 981.185
Flash Point 739.9ºC
Exact Mass 980.402344
PSA 285.00000
LogP 5.46980

 Safety Information

Hazard Codes Xi
Risk Phrases 42/43
Safety Phrases 22-36/37-45-24/25
RIDADR NONH for all modes of transport
HS Code 2941109900

 Customs

HS Code 2941109900

 Synonyms

Penicillin G Benzathine Tetrahydrate
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsäure--N,N'-dibenzylethan-1,2-diamin(2:1)tetrahydrat
acide (2S,5R,6R)-3,3-diméthyl-7-oxo-6-[(phénylacétyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique - N,N'-dibenzyléthane-1,2-diamine (2:1) tétrahydrate
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzyl-1,2-ethanediamine hydrate (2:1:4)
4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, (2S,5R,6R)-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine, hydrate (2:1:4)
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-, (2S,5R,6R)-, compd. with N,N-bis(phenylmethyl)-1,2-ethanediamine, hydrate (2:1:4)
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N'-dibenzylethane-1,2-diamine (2:1) tetrahydrate
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