Penicillin-G

Modify Date: 2026-07-01 20:23:42

Penicillin-G structure	Common Name	Penicillin-G
	CAS Number	61-33-6	Molecular Weight	334.390
	Density	1.4±0.1 g/cm3	Boiling Point	663.3±55.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₈N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	355.0±31.5 °C

Use of Penicillin-G

Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection[1].

Name	benzylpenicillin
Synonym	More Synonyms

Description	Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection[1].
Related Catalog	Research Areas >> Infection
References	[1]. Li D, et al. Determination of penicillin G and its degradation products in a penicillin production wastewater treatment plant and the receiving river. Water Res. 2008 Jan;42(1-2):307-17.

Density	1.4±0.1 g/cm3
Boiling Point	663.3±55.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₈N₂O₄S
Molecular Weight	334.390
Flash Point	355.0±31.5 °C
Exact Mass	334.098724
PSA	112.01000
LogP	1.67
Appearance of Characters	powder
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.655
InChIKey	JGSARLDLIJGVTE-MBNYWOFBSA-N
SMILES	CC1(C)SC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O
Water Solubility	H2O: 100 mg/mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH9400000

CHEMICAL NAME :: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenylacetamido)-

CAS REGISTRY NUMBER :: 61-33-6

BEILSTEIN REFERENCE NO. :: 0044740

LAST UPDATED :: 199612

DATA ITEMS CITED :: 24

MOLECULAR FORMULA :: C16-H18-N2-O4-S

MOLECULAR WEIGHT :: 334.42

WISWESSER LINE NOTATION :: T45 ANV ESTJ CMV1R& F F GVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 15000 units/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Ear) - changes in cochlear structure or function Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 329 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5700 ug/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1118 ug/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 4940 ug/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 653 ug/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 38 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 24 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 104 ku/kg/4D-I

TOXIC EFFECTS :: Blood - changes in other cell count (unspecified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 units/kg/5D-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Immunological Including Allergic - decrease in humoral immune response Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2600 mg/kg/65W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 20 ug/L

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 17,572,1980 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3134 No. of Facilities: 151 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 2695 (estimated) No. of Female Employees: 1750 (estimated)

Hazard Codes	Xn
Risk Phrases	R42/43
Safety Phrases	S36/37
WGK Germany	2
RTECS	XH9700000
HS Code	32041900

Precursor 9
CAS#:551-16-6 6-Aminopenicill... CAS#:5187-94-0 ampicillin Trih... CAS#:103-80-0 Phenylacetyl ch... CAS#:1254-56-4 benzyl 6β-pheny...
CAS#:3956-31-8 benzyl (2S,5R,6... CAS#:36273-76-4 6β-(4-nitro-ben... CAS#:41731-15-1 3-cyclohexyloxy... CAS#:69-53-4 Ampicillin
CAS#:110775-95-6 Sodium 2-(2-ami...
DownStream 8
CAS#:551-16-6 6-Aminopenicill... CAS#:103-82-2 Phenylacetic acid CAS#:52-67-5 D-penicillamine CAS#:13057-98-2 2-Thiazolidinea...
CAS#:3264-88-8 benzylpenicille... CAS#:13093-87-3 5-benzyl-2,2-di... CAS#:113-98-4 Penicillin G po... CAS#:103-81-1 2-Phenylacetamide

HS Code	32041900

Name: Antimicrobial activity against Bifidobacterium thermophilum ATCC 25866
Source: ChEMBL
Target: Bifidobacterium thermophilum
External Id: CHEMBL910836

Name: Antimicrobial activity against Bifidobacterium breve R0070
Source: ChEMBL
Target: Bifidobacterium breve
External Id: CHEMBL910837

Name: Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium animalis ATCC ...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL910838

Name: Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium bifidum R0071 ...
Source: ChEMBL
Target: Bifidobacterium bifidum
External Id: CHEMBL910839

Name: Antimicrobial activity against Bifidobacterium longum ATCC 15708
Source: ChEMBL
Target: Bifidobacterium longum
External Id: CHEMBL910832

Name: Antimicrobial activity against Bifidobacterium longum R0175
Source: ChEMBL
Target: Bifidobacterium longum
External Id: CHEMBL910833

Name: Antimicrobial activity against Bifidobacterium longum P/N 601377
Source: ChEMBL
Target: Bifidobacterium longum
External Id: CHEMBL910834

Name: Antimicrobial activity against Bifidobacterium pseudolongum ATCC 25562
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL910835

Name: Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum ATCC 15...
Source: ChEMBL
Target: Bifidobacterium longum
External Id: CHEMBL910844

Name: Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum R0175 a...
Source: ChEMBL
Target: Bifidobacterium longum
External Id: CHEMBL910845

Total 3076, Current Page 1 of 308

cilloral

MFCD00036193

benzyl penicillin

cosmopen

dropcillin

cilopen

abbocillin

[2S-(2a,5a,6b)]-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

(2S,5R,6R)-6-[(E)-(1-Hydroxy-2-phenylethylidene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

galofak

Penicillin II

Pencillin G

pradupen

Ursopen

penicillin G

UNII-Q42T66VG0C

gelacillin

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

EINECS 204-038-0

pencilling

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Penicillin-G
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Penicillin G
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Penicillin G
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

Penicillin-G suppliers

Penicillin-G price

Penicillin-G

Use of Penicillin-G

Names

Penicillin-G Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Penicillin-GBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.