Anti-inflammatory agent 15

Modify Date: 2024-01-24 09:53:03

Anti-inflammatory agent 15 structure	Common Name	Anti-inflammatory agent 15
	CAS Number	474516-87-5	Molecular Weight	284.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₀N₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anti-inflammatory agent 15

Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research[1].

Name	Anti-inflammatory agent 15

Description	Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	TNF-α
In Vitro	Anti-inflammatory agent 15 (compound 29) is active in the reduction of accumulated nitrite, with an IC50 of 71.7 ± 1.1 μM[1].
References	[1]. Calixto SD, et al. Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis. Bioorg Med Chem. 2022 Jan 1;53:116506.

Molecular Formula	C₁₇H₂₀N₂S
Molecular Weight	284.42

Anti-inflammatory agent 15

Use of Anti-inflammatory agent 15

Names

Anti-inflammatory agent 15 Biological Activity

Chemical & Physical Properties