Anti-inflammatory agent 21

Modify Date: 2024-01-09 15:18:48

Anti-inflammatory agent 21 structure	Common Name	Anti-inflammatory agent 21
	CAS Number	2408836-40-6	Molecular Weight	424.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₁FO₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anti-inflammatory agent 21

Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model[1].

Name	Anti-inflammatory agent 21

Description	Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology
Target	IC50: 0.76 μM (NO)[1]
References	[1]. Chen LZ, Wu J, Li K, et al. Novel phthalide derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo. Eur J Med Chem. 2020;206:112722.

Molecular Formula	C₂₄H₂₁FO₆
Molecular Weight	424.42

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Anti-inflammatory agent 21

Use of Anti-inflammatory agent 21

Names

Anti-inflammatory agent 21 Biological Activity

Chemical & Physical Properties

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