Filipin III
Modify Date: 2024-01-11 00:25:26
Filipin III structure
|
Common Name | Filipin III | ||
|---|---|---|---|---|
| CAS Number | 480-49-9 | Molecular Weight | 654.828 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 913.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C35H58O11 | Melting Point | 163-180°C | |
| MSDS | Chinese USA | Flash Point | 279.3±27.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Filipin IIIFilipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure[1]. |
| Name | filipin III |
|---|---|
| Synonym | More Synonyms |
| Description | Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure[1]. |
|---|---|
| Related Catalog | |
| Target |
Fungal[1] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 913.9±65.0 °C at 760 mmHg |
| Melting Point | 163-180°C |
| Molecular Formula | C35H58O11 |
| Molecular Weight | 654.828 |
| Flash Point | 279.3±27.8 °C |
| Exact Mass | 654.397888 |
| PSA | 208.37000 |
| LogP | -0.41 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.536 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| RTECS | RN9800000 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
CAS#:245681-49-6
CAS#:198955-20-3|
Cholesterol dependence of collagen and echovirus 1 trafficking along the novel α2β1 integrin internalization pathway.
PLoS ONE 8(2) , e55465, (2013) We have previously shown that soluble collagen and a human pathogen, echovirus 1 (EV1) cluster α2β1 integrin on the plasma membrane and cause their internalization into cytoplasmic endosomes. Here we ... |
|
|
Analysis of cholesterol trafficking with fluorescent probes.
Methods Cell Biol. 108 , 367-93, (2012) Cholesterol plays an important role in determining the biophysical properties of biological membranes, and its concentration is tightly controlled by homeostatic processes. The intracellular transport... |
|
|
Influence of membrane cholesterol in the molecular evolution and functional regulation of TRPV4.
Biochem. Biophys. Res. Commun. 456(1) , 312-9, (2015) TRPV4 is involved in several physiological and sensory functions as well as with several diseases and genetic disorders, though the molecular mechanisms for these are unclear. In this work we have ana... |
| Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-, (17E,19E,21E,23E,25E)- |
| (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-Octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one |
| Filipin III |