Bergaptol
Bergaptol structure
|
Common Name | Bergaptol | ||
|---|---|---|---|---|
| CAS Number | 486-60-2 | Molecular Weight | 202.163 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 311.9±11.0 °C at 760 mmHg | |
| Molecular Formula | C11H6O4 | Melting Point | 287-290ºC | |
| MSDS | Chinese USA | Flash Point | 142.4±19.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of BergaptolBergaptolA hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Recent studies suggest that it may have antiproliferative and anticancer properties.target: CYP3A4 [1]IC50: 24.92 [1]For in vivo enzyme activity analysis, 100 μM bergaptol was added to the cultures for an additional 24 h at 37°C. After centrifugation, the supernatant was used to measure the bergapten yield by high performance liquid chromatography (HPLC).[2] |
| Name | bergaptol |
|---|---|
| Synonym | More Synonyms |
| Description | BergaptolA hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Recent studies suggest that it may have antiproliferative and anticancer properties.target: CYP3A4 [1]IC50: 24.92 [1]For in vivo enzyme activity analysis, 100 μM bergaptol was added to the cultures for an additional 24 h at 37°C. After centrifugation, the supernatant was used to measure the bergapten yield by high performance liquid chromatography (HPLC).[2] |
|---|---|
| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 311.9±11.0 °C at 760 mmHg |
| Melting Point | 287-290ºC |
| Molecular Formula | C11H6O4 |
| Molecular Weight | 202.163 |
| Flash Point | 142.4±19.3 °C |
| Exact Mass | 202.026611 |
| PSA | 63.58000 |
| LogP | 0.93 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.711 |
| InChIKey | GIJHDGJRTUSBJR-UHFFFAOYSA-N |
| SMILES | O=c1ccc2c(O)c3ccoc3cc2o1 |
| Storage condition | 2-8°C |
|
~85%
Bergaptol CAS#:486-60-2 |
| Literature: Bellevue III, Frank H.; Woster, Patrick M.; Edwards, David J.; He, Kan; Hollenberg, Paul F. Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 20 p. 2593 - 2598 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: Kozawa; Fukumoto; Matsuyama; Baba Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2712 - 2717 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: Kozawa; Fukumoto; Matsuyama; Baba Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2712 - 2717 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: El-Tawil, B.A.H.; Baghlaf, A.O.; Barbood, S.O. Pharmazie, 1980 , vol. 35, # 8 p. 503 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: Gu; Zhang; Yang; Hattori; Namba Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2498 - 2502 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: Abyshev, A. Z.; Abyshev, D. Z. Chemistry of Natural Compounds, 1983 , vol. 19, # 6 p. 668 - 672 Khimiya Prirodnykh Soedinenii, 1983 , # 6 p. 704 - 709 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: Cesar, Thais B.; Manthey, John A.; Myung, Kyung Journal of Natural Products, 2009 , vol. 72, # 9 p. 1702 - 1704 |
|
~%
Bergaptol CAS#:486-60-2 |
| Literature: Spaeth; Kainrath Chemische Berichte, 1937 , vol. 70, p. 2274 |
![7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[3-[2-(3,3-dimethyloxiranyl)ethyl]-3-methyloxiranyl]methoxy] structure](https://image.chemsrc.com/caspic/374/89787-38-2.png)
| Precursor 8 | |
|---|---|
| DownStream 10 | |
CAS#:482-48-4
CAS#:870653-45-5
CAS#:737-52-0
CAS#:145414-76-2
CAS#:2643-85-8![(7-oxofuro[3,2-g]chromen-4-yl) acetate structure](https://image.chemsrc.com/caspic/168/87997-40-8.png)
CAS#:87997-40-8
CAS#:483-36-3|
Application of the equivalency factor concept to the phototoxicity and –genotoxicity of furocoumarin mixtures
Food Chem. Toxicol. 68 , 257-66, (2014) • The photo-cytotoxic, -mutagenic, and -clastogenic properties in V79 cells of thirteen furocoumarins (FCs), were analyzed. • Nine FC mixtures including one mixture ‘representing’ FCs in Angelica arch... |
|
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
|
|
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
|
|
Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
|
|
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
|
|
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
|
|
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
|
|
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
|
|
Name: Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E...
Source: NCGC
External Id: epac1-activator-v
|
| 4-hydroxyfuranocoumarin |
| 5-Hydroxypsoralen |
| 4-hydroxyfuro[3,2-g]chromen-7-one |
| 4-Hydroxy7H-furo[3,2-g][1]benzopyran-7-one,4-Hydroxybergapten,5-Hydroxy-6,7-furanocoumarin |
| xanthotoxol |
| 5-Hydroxyfuranocoumarin |
| Psoralin,5-hydroxy |
| 4-Hydroxy-7H-furo[3,2-g]chromen-7-one |
| Bergaptol |
| 9-hydroxyfuranocoumarin |
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Bergaptol
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Bergaptol
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- Shanghai Amole Biotechnology Co., Ltd.
- China
- Product Name: Bergaptol
- Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/25mg
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Xiyao Wang
- Email: 3623107365@qq.com
- naturewill
- China
- Product Name: Bergaptol
- Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Bella
- Email: 3157321941@qq.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Bergaptol
- Price: ￥7798.0/10mg ￥3438.0/10mg
- Purity: 98.0%
- Delivery: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
Get all suppliers and price by the below link:
Reference only. check more Bergaptol price